How to select a region using WorldEdit
Use the //wand (normally the wooden axe), left-click a block to select it as position 1 right-click a block to select it as position 2.
OR
Use the commands //pos1 and //pos2 to select the block you are standing on (works with air too).
OR
Use the commands //hpos1 and //hpos2 to select the block you are looking at at a distance.
The selected area is the area or volume between the two positions.